Colorectal Cancer: Symptoms and Lab Tests Explained

Learn about colorectal cancer symptoms, related lab tests, and when to see a doctor.

Sep 5, 2026 3 min read

Colorectal cancer, also known as bowel cancer, affects the colon and rectum. It's important to understand its symptoms and the lab tests used to detect it, as early detection can significantly improve outcomes.

What is colorectal cancer?

Colorectal cancer is a type of cancer that begins in the colon or rectum, parts of the digestive system. It often starts as a polyp, which is a small growth on the inner lining of the colon or rectum. Over time, some polyps can turn into cancer. Knowing the symptoms and getting regular screenings can help catch the disease in its early stages.

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Symptoms of colorectal cancer

Colorectal cancer symptoms can vary, and some people may not experience any symptoms at all in the early stages. Common symptoms include:

  • Changes in bowel habits, such as diarrhea or constipation
  • Blood in the stool, which may make the stool appear dark or cause rectal bleeding
  • Abdominal discomfort, such as cramps, gas, or pain
  • A feeling that the bowel does not empty completely
  • Unexplained weight loss
  • Fatigue or weakness

If you notice any of these symptoms, it's important to talk to your healthcare provider.

Lab tests for detecting colorectal cancer

Several lab tests can help detect colorectal cancer:

  • Fecal occult blood test (FOBT): This test checks for hidden blood in the stool, which can be a sign of cancer or large polyps.
  • Colonoscopy: A procedure where a long, flexible tube with a camera is used to examine the entire colon and rectum. It can also remove polyps for biopsy.
  • Sigmoidoscopy: Similar to a colonoscopy but only examines the lower part of the colon and rectum.
  • Stool DNA test: This test looks for certain DNA markers associated with colorectal cancer in stool samples.

These tests are crucial for early detection and can help determine the best course of treatment.

Risk factors and prevention

Certain factors can increase the risk of developing colorectal cancer, including age, family history, certain genetic syndromes, a diet high in red or processed meats, obesity, smoking, and alcohol use. To lower your risk, consider:

  • Eating a diet rich in fruits, vegetables, and whole grains
  • Engaging in regular physical activity
  • Limiting alcohol consumption and quitting smoking
  • Undergoing regular screenings as recommended by your healthcare provider

Frequently asked questions

What age should I start getting screened for colorectal cancer? Most guidelines recommend starting regular screenings at age 45, but those with higher risk factors may need to start earlier. Consult your healthcare provider for personalized advice.

Is a colonoscopy painful? A colonoscopy is generally not painful, as patients are often sedated during the procedure. Some may experience mild discomfort or cramping afterward.

Can colorectal cancer be cured? When detected early, colorectal cancer can often be treated successfully. Treatment options depend on the stage of the cancer and may include surgery, chemotherapy, radiation, or a combination of these.

When to see a doctor

If you experience any symptoms of colorectal cancer, such as changes in bowel habits or blood in your stool, it is important to consult a healthcare provider. Early detection through screening can significantly improve treatment outcomes.

Disclaimer: This article is for informational purposes only and does not replace professional medical advice. Decisions about your health should be made with your healthcare provider.

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