Preparing for a Faecal Calprotectin Test: Fasting, Timing, and Factors

Learn how to prepare for a faecal calprotectin test, including fasting, timing, and factors affecting results.

Aug 14, 2026 3 min read

A faecal calprotectin test measures the level of calprotectin in your stool, which helps indicate inflammation in your intestines. This test is often used to help diagnose inflammatory bowel disease (IBD) and to differentiate it from irritable bowel syndrome (IBS). Proper preparation can ensure the most accurate results.

What is a Faecal Calprotectin Test?

A faecal calprotectin test is a non-invasive laboratory test that measures the amount of calprotectin in your stool. Calprotectin is a protein released by white blood cells when there is inflammation in the intestines. Elevated levels of calprotectin can suggest the presence of conditions like Crohn's disease or ulcerative colitis, both types of inflammatory bowel disease (IBD).

Importance of Proper Test Preparation

Accurate preparation for a faecal calprotectin test is crucial because various factors can affect the results. The test helps differentiate between IBD and IBS, conditions that have overlapping symptoms but require different treatments. Ensuring that the test results are as accurate as possible is important for guiding further diagnostic steps and treatment plans.

Fasting and Dietary Considerations

Unlike many blood tests, the faecal calprotectin test does not typically require fasting. However, it is advisable to maintain a consistent diet in the days leading up to the test. Sudden changes in diet might influence the results, so eating your usual meals is recommended. Additionally, avoid taking non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, as they can artificially raise calprotectin levels.

Timing of the Test

Timing can be an important factor in faecal calprotectin testing. The test is often scheduled when symptoms are at their peak to capture the most accurate reflection of intestinal inflammation. Discuss with your healthcare provider the best time to collect the stool sample based on your symptoms. Samples should be collected in a clean, dry container and sent to the lab as soon as possible to prevent degradation of the sample.

Factors That Can Skew Results

Several factors can skew the results of a faecal calprotectin test:

  • Medications: As mentioned, NSAIDs can increase calprotectin levels. Be sure to inform your healthcare provider about any medications you are taking.
  • Gastrointestinal Infections: Recent infections can elevate calprotectin levels. If you've had a stomach bug or food poisoning, let your doctor know.
  • Physical Activity: Intense exercise can sometimes affect test results, so it might be best to avoid strenuous activities shortly before collecting the sample.

Frequently Asked Questions

How long does it take to get results? Results from a faecal calprotectin test are usually available within a few days to a week, depending on the lab processing the sample.

Can I take my regular medications before the test? It’s important to inform your doctor about all medications you are taking. Some, like NSAIDs, may need to be paused before the test.

What if my results are elevated? Elevated results may indicate inflammation in your intestines. Your doctor will use these results along with other tests and evaluations to determine the cause.

When to See a Doctor

If you experience symptoms such as persistent abdominal pain, diarrhea, or unexplained weight loss, it’s important to consult a healthcare provider. These symptoms can be indicative of underlying intestinal conditions that may require further investigation.

Remember, this information is intended to help you understand the test better, but any decisions about your health should be made in consultation with your healthcare provider.

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