Flank Pain: Key Blood Markers to Check

Flank pain can be a sign of various conditions. Learn which blood markers are important to check when experiencing this symptom.

Sep 18, 2026 3 min read

Flank pain, also known as loin pain, is discomfort or pain in the area on the side of your body between the ribs and the hip. It can be a result of various conditions affecting the kidneys, urinary tract, or other organs. Understanding which blood markers to check can help identify the underlying cause of flank pain.

What is flank pain?

Flank pain refers to discomfort in the area between the lower ribs and the hip. This type of pain can be sharp, dull, or cramping and may occur on one or both sides of the body. It can be associated with conditions like kidney stones, infections, or other issues within the urinary system.

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Why do blood markers matter for flank pain?

Blood markers are substances measured in your blood that can provide valuable information about your health. When experiencing flank pain, certain blood markers can help determine the cause. These markers can indicate infection, inflammation, or other abnormalities that might be affecting your kidneys or urinary tract.

Key blood markers to check

Creatinine

Creatinine is a waste product produced by muscle metabolism and is filtered out of the blood by the kidneys. Elevated levels of creatinine in the blood can indicate impaired kidney function, which might be related to the cause of flank pain.

Blood Urea Nitrogen (BUN)

Blood urea nitrogen is another waste product filtered by the kidneys. High levels of BUN can suggest kidney dysfunction or dehydration, both of which can be associated with flank pain.

White Blood Cell Count (WBC)

A white blood cell count measures the number of white blood cells in your blood. An elevated WBC count can indicate an infection or inflammation, such as a urinary tract infection or kidney infection, which can cause flank pain.

C-Reactive Protein (CRP)

C-reactive protein is a marker of inflammation in the body. High levels of CRP can suggest inflammation due to infection or other conditions affecting the kidneys or urinary tract.

Frequently asked questions

What are common causes of flank pain? Flank pain can be caused by kidney stones, urinary tract infections, kidney infections, or other conditions affecting the urinary system.

Can blood tests alone diagnose the cause of flank pain? Blood tests can provide important clues, but they are often used alongside other diagnostic tools like imaging studies to determine the exact cause of flank pain.

Are there other tests besides blood markers for flank pain? Yes, urine tests and imaging studies such as ultrasounds or CT scans may also be used to diagnose the cause of flank pain.

When to see a doctor

If you experience severe flank pain, especially if it is accompanied by symptoms such as fever, nausea, vomiting, or blood in the urine, it is important to seek medical attention. These symptoms could indicate a serious condition that requires prompt evaluation and treatment.

Remember, the information provided here is for educational purposes only. Always discuss your health concerns and test results with your healthcare provider.

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