Understanding Gallstones: A Patient's Guide to Cholelithiasis

Gallstones, also known as cholelithiasis, are solid particles that form in the gallbladder. Learn what they are, why they matter, and when to consult a doctor.

Aug 30, 2026 3 min read

Gallstones, medically known as cholelithiasis, are small, hard deposits that form in the gallbladder, a small organ located under the liver. These stones can vary in size and may cause no symptoms or lead to significant discomfort and complications. Understanding gallstones is important for managing your health and knowing when to seek medical attention.

What are gallstones?

Gallstones are solid particles that develop from bile, a digestive fluid produced by the liver and stored in the gallbladder. They can be made up of cholesterol, bilirubin (a byproduct of red blood cell breakdown), or a combination of these substances. Cholesterol gallstones are the most common type, accounting for about 80% of cases.

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Why do gallstones matter?

While gallstones themselves may not always cause symptoms, they can lead to complications if they obstruct the bile ducts, which are tubes that carry bile from the liver and gallbladder to the small intestine. This blockage can cause pain, inflammation, and infection. In severe cases, it can lead to conditions such as acute cholecystitis (inflammation of the gallbladder), pancreatitis (inflammation of the pancreas), or cholangitis (infection of the bile duct).

What causes gallstones to form?

Gallstones can form when there is an imbalance in the substances that make up bile. Factors that contribute to this imbalance include:

  • Excess cholesterol in bile: When the liver excretes more cholesterol than bile can dissolve, it can form crystals that eventually become stones.
  • Excess bilirubin: Certain medical conditions, such as liver cirrhosis or blood disorders, can cause the liver to produce too much bilirubin, leading to pigment gallstones.
  • Incomplete emptying of the gallbladder: If the gallbladder does not empty completely or frequently enough, bile can become concentrated and form stones.

Recognizing symptoms of gallstones

Many people with gallstones experience no symptoms and may not even know they have them. However, when symptoms do occur, they can include:

  • Sudden and intense pain in the upper right abdomen or center of the abdomen
  • Pain between the shoulder blades or in the right shoulder
  • Nausea or vomiting
  • Jaundice (yellowing of the skin and eyes) if a bile duct becomes blocked

Frequently asked questions

What are the risk factors for developing gallstones? Risk factors include obesity, a high-fat diet, rapid weight loss, pregnancy, certain medical conditions, and a family history of gallstones.

Can gallstones be prevented? While not all gallstones can be prevented, maintaining a healthy weight, eating a balanced diet, and exercising regularly can reduce the risk.

How are gallstones diagnosed? Gallstones are typically diagnosed through imaging tests such as an ultrasound or CT scan, which can reveal the presence of stones in the gallbladder.

What are the treatment options for gallstones? Treatment may include lifestyle changes, medications to dissolve stones, or surgical removal of the gallbladder (cholecystectomy) if symptoms are severe.

Do gallstones always require treatment? Not always. If gallstones are not causing symptoms, they may not need immediate treatment, but monitoring by a healthcare provider is important.

When to see a doctor

If you experience sudden, intense abdominal pain, especially in the upper right section, or if you have symptoms like jaundice or persistent nausea, it is important to consult a healthcare provider. These symptoms could indicate a serious complication that requires medical attention.

Remember, this information is for educational purposes only and any medical decisions should be made in consultation with your healthcare provider.

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