Why is Bilirubin High? Causes, Symptoms, and What to Do

Discover why bilirubin levels might be high, what symptoms to watch for, and what steps to take.

Aug 1, 2026 3 min read

When you receive lab results showing high bilirubin levels, it can be concerning. Bilirubin is a yellow compound that occurs in the body as a byproduct of the normal breakdown of red blood cells. Understanding why your bilirubin levels are elevated can help you and your healthcare provider decide on the best course of action.

What is Bilirubin?

Bilirubin is a substance produced during the normal breakdown of red blood cells. It passes through the liver and is eventually excreted from the body. Normally, bilirubin levels in the blood are low, but when they are high, it can indicate a problem with the liver, gallbladder, or red blood cells. A bilirubin test measures the amount of this substance in your blood, and results are typically reported in milligrams per deciliter (mg/dL).

Why High Bilirubin Matters

Elevated bilirubin levels can be a sign of various health issues. It may indicate liver diseases such as hepatitis or cirrhosis, where the liver is unable to process bilirubin effectively. High bilirubin can also result from conditions like hemolytic anemia, where red blood cells are broken down too quickly, or bile duct obstruction, which prevents bilirubin from being excreted properly. In newborns, high bilirubin levels can lead to jaundice, a condition where the skin and eyes turn yellow.

Causes of High Bilirubin

Several factors can cause high bilirubin levels:

  • Liver Diseases: Conditions like hepatitis, cirrhosis, or liver cancer can impair the liver's ability to process bilirubin.
  • Hemolytic Anemia: This condition causes the rapid breakdown of red blood cells, leading to increased bilirubin production.
  • Bile Duct Obstruction: Gallstones or tumors can block bile ducts, preventing bilirubin from leaving the liver.
  • Genetic Disorders: Conditions like Gilbert's syndrome, a common genetic liver disorder, can cause mild elevations in bilirubin.
  • Newborn Jaundice: In infants, the liver may not be mature enough to handle bilirubin efficiently, leading to temporary high levels.

Symptoms of High Bilirubin

High bilirubin levels can cause a range of symptoms, though some people may not experience any noticeable signs. Common symptoms include:

  • Jaundice: Yellowing of the skin and eyes.
  • Dark Urine: Bilirubin can cause urine to become darker in color.
  • Fatigue: Feeling unusually tired or weak.
  • Abdominal Pain: Discomfort or pain in the abdomen, particularly if related to liver or gallbladder issues.

What to Do if Your Bilirubin is High

If your bilirubin levels are high, your healthcare provider may recommend further testing to identify the underlying cause. This might include liver function tests, a complete blood count (CBC), or imaging studies like an ultrasound. Treatment will depend on the cause of the elevated bilirubin. For instance, if a bile duct obstruction is causing the problem, surgery may be necessary. If liver disease is the issue, lifestyle changes and medication might be recommended.

Frequently Asked Questions

What is considered a high bilirubin level? Bilirubin levels above the normal range, which is typically up to 1.2 mg/dL for adults, are considered high. However, the exact threshold can vary slightly between labs.

Can high bilirubin levels be lowered naturally? Lifestyle changes such as a balanced diet, regular exercise, and avoiding alcohol can support liver health, potentially helping to lower bilirubin levels. However, it's important to address any underlying medical conditions.

Is high bilirubin always serious? Not necessarily. Mildly elevated bilirubin levels, especially in conditions like Gilbert's syndrome, are often harmless. However, significant or persistent elevations should be evaluated by a healthcare provider.

When to See a Doctor

You should consult a healthcare provider if you experience symptoms of high bilirubin such as jaundice, dark urine, or unexplained fatigue. Additionally, if you have a known liver condition or a history of elevated bilirubin, regular monitoring and medical advice are important to manage your health effectively.

Remember, while this information is intended to be informative, any decisions regarding your health should be made in consultation with your healthcare provider.

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