How to Prepare for a Red Cell Distribution Width (RDW) Blood Test

Learn how to prepare for an RDW blood test, including fasting, timing, and factors that may affect your results.

Aug 4, 2026 2 min read

The Red Cell Distribution Width (RDW) blood test is a part of a complete blood count (CBC) that measures the variation in the size of your red blood cells. It can help diagnose different types of anemia and other health conditions. Proper preparation can ensure accurate results.

What is an RDW Blood Test?

The RDW test measures the range of sizes of your red blood cells. Typically, red blood cells should be of a uniform size to efficiently transport oxygen throughout your body. A high RDW value indicates a greater variation in cell sizes, which can be a sign of certain health issues, such as anemia or nutrient deficiencies.

Why Does RDW Matter?

Understanding your RDW levels can provide insights into your overall health. Abnormal RDW values can suggest the presence of conditions like iron deficiency anemia, vitamin B12 deficiency, or even chronic liver disease. Therefore, knowing your RDW can help in the early detection and management of these conditions.

Preparing for the RDW Test

Fasting and Timing

The RDW test itself does not require fasting. However, if it's part of a broader panel of tests, such as a comprehensive metabolic panel (CMP), fasting might be necessary. It's best to follow your healthcare provider's instructions regarding fasting.

Factors That Can Affect the Results

Several factors can skew RDW results:

  • Recent Blood Transfusion: Receiving a blood transfusion can temporarily affect RDW values.
  • Pregnancy: Hormonal changes during pregnancy can alter red blood cell size, impacting RDW.
  • Dietary Factors: A diet low in iron, vitamin B12, or folate can influence RDW levels.
  • Medications: Certain medications, such as chemotherapy drugs, can affect red blood cell production and size.

Understanding Your RDW Results

RDW results are typically reported as a percentage. A normal range is generally between 11.5% and 14.5%, but this can vary slightly depending on the laboratory. A higher RDW value may indicate a greater diversity in red blood cell size, which can be a clue to various underlying conditions.

Frequently Asked Questions

Can I eat before an RDW test? Yes, you can eat before an RDW test unless it's part of a panel that requires fasting.

What should I do if my RDW is high? A high RDW can indicate a variety of conditions. Discuss the results with your healthcare provider to determine the next steps.

Does dehydration affect RDW levels? Dehydration can concentrate the blood, potentially affecting RDW results. Stay well-hydrated before the test.

When to See a Doctor

If your RDW results are outside the normal range, it's important to consult with your healthcare provider. They can help interpret the results in the context of your overall health and decide if further testing is necessary.

This information is not a substitute for professional medical advice. Always consult your healthcare provider for any health concerns.

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