What is Reactive Arthritis? A Patient's Guide to the Condition

Learn about reactive arthritis, its causes, symptoms, and when to consult a doctor for this condition.

Sep 11, 2026 3 min read

Reactive arthritis is a type of inflammatory arthritis that occurs as a reaction to an infection in another part of the body, often the intestines, genitals, or urinary tract. It is part of a group of conditions known as spondyloarthritis, which are linked by common clinical features. Understanding reactive arthritis can help you recognize its symptoms and seek appropriate care.

What is Reactive Arthritis?

Reactive arthritis is a joint inflammation that occurs after an infection, typically within a few weeks. It is not caused directly by the infection in the joint but is instead a reaction to the infection elsewhere in the body. Common infections that can trigger reactive arthritis include gastrointestinal infections like salmonella or sexually transmitted infections such as chlamydia. The condition is more common in young adults and tends to affect men more than women.

Have your own lab results? Upload your report and get a clear, private AI explanation in minutes - free, in English, Russian or Hebrew.
Analyze my results

Symptoms of Reactive Arthritis

The symptoms of reactive arthritis can vary but often include joint pain and swelling, especially in the knees, ankles, and feet. You may also experience inflammation of the eyes (conjunctivitis), urinary problems, and skin rashes. The symptoms usually develop within 1 to 4 weeks after the infection and can last for several months. In some cases, the symptoms may become chronic or recur over time.

Causes and Risk Factors

The exact cause of reactive arthritis is not fully understood, but it is believed to involve an immune system response to an infection. Some people may have a genetic predisposition, particularly those who carry the HLA-B27 gene. This gene is associated with a higher risk of developing reactive arthritis and other types of spondyloarthritis. Risk factors include a recent infection, particularly of the gastrointestinal or genitourinary tract, and a family history of arthritis.

Diagnosis and Treatment

Diagnosing reactive arthritis typically involves a medical history review, physical examination, and laboratory tests to identify recent infections and rule out other types of arthritis. There is no single test for reactive arthritis, but tests may include blood tests for inflammation markers and genetic testing for the HLA-B27 gene.

Treatment focuses on managing symptoms and may include nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce pain and swelling, corticosteroids for severe inflammation, and antibiotics if a bacterial infection is still present. Physical therapy can also help maintain joint function and prevent stiffness.

Frequently Asked Questions

What triggers reactive arthritis? Reactive arthritis is triggered by an infection in another part of the body, such as the intestines or urinary tract. Common triggers include gastrointestinal infections and sexually transmitted infections.

Is reactive arthritis contagious? No, reactive arthritis itself is not contagious. However, the infections that trigger it can be spread from person to person.

Can reactive arthritis be cured? There is no cure for reactive arthritis, but the symptoms can be managed with treatment. Many people recover completely, though some may experience recurring symptoms.

How long does reactive arthritis last? Symptoms of reactive arthritis can last from a few months to a year. In some cases, symptoms may become chronic or recur over time.

Does reactive arthritis affect other parts of the body? Yes, in addition to joints, reactive arthritis can affect the eyes, skin, and urinary tract.

When to See a Doctor

If you experience joint pain and swelling after a recent infection, especially if accompanied by eye inflammation or urinary problems, it is important to see a healthcare provider. Early diagnosis and treatment can help manage symptoms and prevent complications. Always consult a healthcare professional for personalized advice and treatment.

Decisions about your health should be made in consultation with your healthcare provider.

Read this in another language

Doctor reviews: 0 - pending

This explainer is queued for our doctor panel and hasn't been individually reviewed yet. It's general information, drawn from standard references - always confirm decisions with your own clinician.

Have your own lab results? Upload your report and get a clear, private AI explanation in minutes - free, in English, Russian or Hebrew.
Analyze my results