Urticaria (Hives): Symptoms and the Lab Tests Behind Them

Learn about urticaria, also known as hives, its symptoms, causes, and the lab tests used to diagnose this common skin condition.

Sep 1, 2026 3 min read

Urticaria, commonly known as hives, is a skin condition characterized by red, itchy welts that can appear anywhere on the body. While hives are often harmless and resolve on their own, they can be uncomfortable and sometimes indicate an underlying health issue.

What is Urticaria?

Urticaria is a skin reaction that results in raised, itchy welts, also known as wheals, on the skin. These welts can vary in size and appear anywhere on the body. They may be caused by an allergic reaction, stress, infections, or other triggers. Urticaria is classified into acute and chronic types: acute urticaria lasts less than six weeks, while chronic urticaria persists for six weeks or longer.

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Symptoms of Urticaria

The primary symptom of urticaria is the appearance of welts on the skin. These welts are usually red, raised, and can be very itchy. Other symptoms may include:

  • Swelling of the skin, known as angioedema, especially around the eyes, lips, and throat.
  • Burning or stinging sensation.
  • Welts that vary in size and shape, and may change location over time.

Causes and Triggers

Urticaria can be triggered by a variety of factors, including:

  • Allergens such as food, medications, or insect stings.
  • Physical stimuli like pressure, temperature changes, or sunlight.
  • Stress or anxiety.
  • Infections or illnesses, like a cold or flu.
  • Autoimmune disorders.

Lab Tests for Diagnosing Urticaria

While urticaria is often diagnosed based on symptoms and medical history, lab tests can help identify underlying causes. Common tests include:

  • Allergy tests: These may include skin prick tests or specific IgE blood tests to identify allergens.
  • Complete blood count (CBC): This test can help rule out infections or other blood-related conditions.
  • Autoimmune tests: For chronic urticaria, tests like antinuclear antibody (ANA) may be conducted to check for autoimmune diseases.
  • Thyroid function tests: Since thyroid disorders can sometimes cause chronic urticaria, these tests may be recommended.

Frequently Asked Questions

What should I do if I suspect I have hives? If you notice red, itchy welts on your skin, consider any recent exposure to potential triggers, such as new foods or medications. Keeping a diary of these exposures can help identify triggers.

Can hives be a sign of a serious condition? While hives are usually not serious, they can sometimes indicate an underlying condition such as an autoimmune disorder or a severe allergic reaction.

How are hives treated? Treatment often includes antihistamines to relieve itching and swelling. In severe cases, a doctor may prescribe corticosteroids or other medications.

When to See a Doctor

You should consider seeing a doctor if:

  • The hives persist for more than a few days.
  • You experience difficulty breathing or swallowing, which could indicate a severe allergic reaction.
  • The hives recur frequently or are accompanied by other symptoms, such as fever or joint pain.
  • The hives are painful or develop blisters.

While this article provides information on urticaria and related tests, decisions about your health should always be made in consultation with a healthcare provider.

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