What is Pericarditis? A Patient's Guide to the Condition

Pericarditis is inflammation of the pericardium, the sac surrounding the heart. Learn about its causes, symptoms, and when to consult a doctor.

Sep 9, 2026 3 min read

Pericarditis is a condition characterized by inflammation of the pericardium, which is the thin, sac-like membrane surrounding your heart. This condition can be caused by a variety of factors, including infections, autoimmune diseases, and heart attacks. Understanding pericarditis is important because it can affect heart function and lead to complications if not managed properly.

What is pericarditis?

The pericardium is a double-layered sac that encases the heart, providing it with protection and support. Pericarditis occurs when this sac becomes inflamed, often resulting in chest pain and other symptoms. The inflammation can be acute, lasting less than three weeks, or chronic, persisting for months. Acute pericarditis is more common and often resolves on its own, while chronic pericarditis may require more intensive treatment.

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Causes of pericarditis

Several factors can lead to pericarditis:

  • Infections: Viral infections are the most common cause, but bacterial, fungal, and parasitic infections can also lead to pericarditis.
  • Autoimmune diseases: Conditions like lupus or rheumatoid arthritis can cause the immune system to attack the pericardium.
  • Heart attack: Damage to the heart muscle can lead to inflammation of the pericardium.
  • Trauma or injury: Physical injury to the chest can cause pericarditis.
  • Other medical conditions: Kidney failure, cancer, and certain medications can also contribute to pericarditis.

Symptoms of pericarditis

The most common symptom of pericarditis is sharp, stabbing chest pain that may worsen with deep breaths or lying down. Other symptoms include:

  • Fever
  • Weakness or fatigue
  • Cough
  • Swelling in the abdomen or legs
  • Difficulty breathing, especially when lying flat

These symptoms can vary depending on the underlying cause and the severity of the inflammation.

Diagnosing pericarditis

If pericarditis is suspected, your doctor may order several tests to confirm the diagnosis and determine the cause. These tests can include:

  • Electrocardiogram (ECG): Measures the electrical activity of the heart and can show characteristic changes in pericarditis.
  • Echocardiogram: Uses ultrasound waves to create an image of the heart and can reveal fluid accumulation around the heart.
  • Chest X-ray: Can show changes in the size and shape of the heart.
  • Blood tests: These can help identify markers of inflammation, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), and detect infections or autoimmune diseases.

Treatment options

Treatment for pericarditis focuses on reducing inflammation and relieving symptoms. Common treatments include:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): These medications help reduce inflammation and pain.
  • Colchicine: Often used alongside NSAIDs to prevent recurrence of pericarditis.
  • Corticosteroids: Used when other treatments are not effective, but they are generally avoided due to potential side effects.
  • Antibiotics or antifungal medications: Prescribed if an infection is the cause of pericarditis.

In rare cases, surgery may be needed to remove excess fluid from the pericardium or to remove the pericardium itself if it becomes thickened and rigid.

Frequently asked questions

What is the prognosis for pericarditis?

Most people with acute pericarditis recover completely with treatment. Chronic pericarditis may require ongoing management but can often be controlled with medication.

Can pericarditis recur?

Yes, pericarditis can recur, especially if the underlying cause is not addressed. Colchicine is often used to help prevent recurrences.

Is pericarditis life-threatening?

Pericarditis is rarely life-threatening, but complications like cardiac tamponade (pressure on the heart due to fluid buildup) can be serious and require immediate medical attention.

When to see a doctor

You should see a doctor if you experience persistent chest pain, especially if it is sharp and worsens with breathing or lying down. Seek immediate medical attention if you have difficulty breathing, a rapid or irregular heartbeat, or swelling in your legs or abdomen.

Remember, this information serves as a guide and should not replace professional medical advice. Always consult with your healthcare provider for personalized care and treatment options.

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