Why Are Neutrophils Low? Causes, Symptoms, and What to Do

Low neutrophils can indicate various health issues. Understand the causes, symptoms, and when to consult a doctor.

Aug 9, 2026 3 min read

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Neutrophils are a type of white blood cell that play a crucial role in fighting infections. If you've been told your neutrophil count is low, you might be wondering what this means for your health. This article will explore the potential causes, symptoms, and steps you can take if your neutrophil count is below the typical range of ~2.0–7.5 ×10^9/L.

What are neutrophils?

Neutrophils are the most abundant type of white blood cells in your body. They are part of the immune system and help protect against infections by destroying bacteria and fungi. Neutrophils are a type of granulocyte, and their count is typically included in a full blood count differential. A normal neutrophil count for adults is approximately ~2.0–7.5 ×10^9/L. When the count falls below this range, it is referred to as neutropenia.

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Causes of low neutrophils

There are several reasons why your neutrophil count might be low. Some common causes include:

  • Infections: Viral infections, such as the flu or hepatitis, can temporarily lower neutrophil levels.
  • Autoimmune disorders: Conditions like lupus or rheumatoid arthritis can cause the body to attack its own neutrophils.
  • Bone marrow disorders: Diseases affecting bone marrow, such as leukemia or aplastic anemia, can result in low neutrophil production.
  • Medications: Certain medications, including chemotherapy drugs, can reduce neutrophil counts as a side effect.
  • Nutritional deficiencies: Lack of essential nutrients like vitamin B12 or folate can affect neutrophil production.

Symptoms of low neutrophils

Low neutrophil levels, or neutropenia, might not always cause noticeable symptoms. However, if you have a significantly low count, you might experience:

  • Frequent infections
  • Fever
  • Mouth ulcers
  • Sore throat

These symptoms occur because the immune system is less effective at fighting off infections when neutrophil levels are low.

What to do if your neutrophil count is low

If your neutrophil count is below the normal range of ~2.0–7.5 ×10^9/L, it's important to work with your healthcare provider to determine the cause. They may conduct additional tests to identify underlying conditions or adjust any medications that might be contributing to the low count. Maintaining good hygiene, staying up to date with vaccinations, and eating a balanced diet can also help support your immune system.

When to see a doctor

You should consult a healthcare provider if you experience frequent or severe infections, persistent fever, or any other concerning symptoms. It is especially important to seek medical advice if you have been diagnosed with a condition known to affect neutrophil levels or if you are undergoing treatments like chemotherapy that can impact your blood counts.

Frequently asked questions

What is considered a low neutrophil count?
A neutrophil count below ~2.0 ×10^9/L is generally considered low. This condition is known as neutropenia.

Can stress cause low neutrophils?
While stress can affect the immune system, it is not a common direct cause of low neutrophil levels. However, chronic stress can impact overall health and potentially contribute to immune system issues.

How are low neutrophils treated?
Treatment depends on the underlying cause. It may involve addressing nutritional deficiencies, adjusting medications, or treating any infections or underlying conditions.

Can a low neutrophil count be temporary?
Yes, a low neutrophil count can be temporary, especially if it is caused by a recent infection or medication. Your healthcare provider can help determine if the low count is temporary or if further investigation is needed.

Is it dangerous to have low neutrophils?
Having low neutrophils can increase your risk of infections, which can be serious. It's important to work with your healthcare provider to manage the condition effectively.

Can diet improve neutrophil levels?
A balanced diet rich in essential nutrients can support overall immune function, but it may not directly increase neutrophil levels if there are other underlying causes.

Disclaimer

This information is intended to help you understand your lab results and is not a substitute for professional medical advice. Always consult your doctor or healthcare provider for decisions about your health.

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