Lab marker · Low

Low Estimated GFR (eGFR): what it means

A Estimated GFR (eGFR) result below the normal range is considered low. Here is what a reduced Estimated GFR (eGFR) can point to, and when it is worth discussing with a doctor.

Reference range: ≥90 normal; 60–89 mildly reduced; <60 chronic kidney disease threshold

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What a low Estimated GFR (eGFR) can mean

  • eGFR 60–89 — mildly reduced; often age-related, monitored.
  • eGFR 45–59 (CKD G3a) — moderately reduced; primary-care management plus annual specialist input.
  • eGFR 30–44 (CKD G3b) — nephrology referral.
  • eGFR <30 (CKD G4–G5) — advanced kidney disease; preparation for renal replacement planning.
  • Causes: diabetes, hypertension, glomerulonephritis, obstruction, drug toxicity.

When to discuss with a doctor

A single low eGFR isn't a diagnosis — chronic kidney disease requires the reduction to persist for ≥3 months. Sustained eGFR <60 warrants primary-care work-up: urine albumin/creatinine ratio, blood pressure control, medication review (avoid NSAIDs, dose-adjust as needed). eGFR <30 needs a nephrologist. Mediora.AI plots your eGFR trajectory; treatment is highly individualised.

Conditions this can relate to

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Mediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.