Lab marker · High

High Insulin-like Growth Factor 1 (IGF-1): what it means

A Insulin-like Growth Factor 1 (IGF-1) result above the normal range is considered high. Here is what a raised Insulin-like Growth Factor 1 (IGF-1) can point to, and when it is worth discussing with a doctor.

Reference range: Age-dependent; ~100–300 ng/mL in young adults; declines with age

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What a high Insulin-like Growth Factor 1 (IGF-1) can mean

  • Acromegaly / gigantism — pituitary adenoma; IGF-1 above age-matched range, often paired with insulin resistance.
  • Puberty / pregnancy — physiological surge.
  • Hyperthyroidism, obesity (mild) — modest elevation.
  • Exogenous GH therapy — therapeutic monitoring above the normal range warrants dose reduction.

When to discuss with a doctor

IGF-1 outside age-matched range warrants endocrinology follow-up: high → screen for pituitary adenoma (MRI + oral glucose suppression test); low → assess pituitary function (GH stimulation test). Self-supplementation with GH or IGF-1 is dangerous and unregulated. Mediora.AI surfaces the value against the age band; treatment changes belong with an endocrinologist.

Conditions this can relate to

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Mediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.