Low Immunoglobulin G (IgG): what it means
A Immunoglobulin G (IgG) result below the normal range is considered low. Here is what a reduced Immunoglobulin G (IgG) can point to, and when it is worth discussing with a doctor.
Reference range: ~7–16 g/L in adults; the main antibody of long-term immunity; a low level can mean immune deficiency, a high one chronic infection or inflammation
Understand your full resultWhat a low Immunoglobulin G (IgG) can mean
- Antibody (immune) deficiency — inherited (common variable immunodeficiency) or acquired; important because it can cause recurrent infections and may be treatable with immunoglobulin replacement.
- Protein loss — from the kidneys (nephrotic syndrome) or gut.
- Some medications and blood conditions.
When to discuss with a doctor
Total IgG is worth checking in someone with recurrent, severe or unusual infections, where a low level can reveal a treatable antibody deficiency and prompt referral to immunology. It is also part of the work-up for a raised total protein or suspected myeloma, where a monoclonal IgG on protein electrophoresis needs specialist assessment. A broadly raised IgG usually reflects chronic infection, inflammation or liver disease and is interpreted in that context. IgG is read together with IgA and IgM. Mediora.AI shows IgG alongside the other immunoglobulins so the antibody pattern is visible; the interpretation belongs with your doctor.
Conditions this can relate to
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Upload your test - freeMediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.