Lab marker · Low

Low Parathyroid Hormone (PTH): what it means

A Parathyroid Hormone (PTH) result below the normal range is considered low. Here is what a reduced Parathyroid Hormone (PTH) can point to, and when it is worth discussing with a doctor.

Reference range: 15–65 pg/mL (intact PTH assay)

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What a low Parathyroid Hormone (PTH) can mean

  • Hypoparathyroidism — surgical (post-thyroidectomy is the commonest), autoimmune, congenital (DiGeorge syndrome).
  • Hypercalcaemia of malignancy — PTHrP from tumour suppresses the real PTH; calcium high, PTH suppressed.
  • Severe hypomagnesaemia — magnesium is needed for PTH secretion; correct magnesium first.

When to discuss with a doctor

Persistent calcium >10.5 mg/dL or symptoms of kidney stones, bone pain, abdominal pain, fatigue or depression warrant PTH + 25-OH vitamin D + 24-hour urine calcium. Primary hyperparathyroidism with classical symptoms is a surgical referral. Mediora.AI shows PTH alongside calcium and vitamin D; treatment decisions belong with endocrinology.

Conditions this can relate to

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Mediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.