Low Vasoactive intestinal peptide (VIP): what it means
A Vasoactive intestinal peptide (VIP) result below the normal range is considered low. Here is what a reduced Vasoactive intestinal peptide (VIP) can point to, and when it is worth discussing with a doctor.
Reference range: reference varies by assay (often <30 pmol/L); a markedly high level suggests a VIP-secreting tumour (VIPoma) causing profuse watery diarrhoea and low potassium
Understand your full resultWhat a low Vasoactive intestinal peptide (VIP) can mean
- Normal or low — the expected result; makes a VIPoma very unlikely and points diarrhoea toward commoner causes.
When to discuss with a doctor
Blood VIP is a highly targeted specialist test, not a routine one — it is ordered in the specific setting of severe, persistent, watery diarrhoea that continues despite fasting and is often accompanied by a low potassium, once the common causes have been excluded. A markedly high fasting level in that context suggests a VIPoma, a rare tumour needing specialist diagnosis (with imaging) and treatment, alongside urgent correction of the fluid and potassium losses, which can themselves be dangerous. Mediora.AI can surface a raised VIP and the accompanying low-potassium pattern from your results and flag it for review, but confirming a VIPoma is a specialist assessment — the interpretation belongs with your doctor.
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Upload your test - freeMediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.