Lab marker · Low

Low Vitamin D (25-OH): what it means

A Vitamin D (25-OH) result below the normal range is considered low. Here is what a reduced Vitamin D (25-OH) can point to, and when it is worth discussing with a doctor.

Reference range: Deficient <20, insufficient 20–30, optimal 30–60, high >100 ng/mL

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What a low Vitamin D (25-OH) can mean

  • Limited sun exposure — northern latitudes, indoor lifestyle, heavy sunscreen use, dark skin pigmentation.
  • Malabsorption — coeliac disease, Crohn's, gastric bypass.
  • Obesity — vitamin D distributes into adipose tissue, lowering serum levels.
  • Chronic kidney or liver disease — reduced conversion.

When to discuss with a doctor

Levels below 20 ng/mL meet the deficiency threshold most clinicians act on with supplementation; below 30 ng/mL is the insufficient zone where many guidelines also recommend a course. Mediora.AI surfaces your reading against these thresholds. Discuss dose and duration with your clinician — high-dose self-supplementation without monitoring carries a hypercalcaemia risk.

Conditions this can relate to

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Mediora.AI is informational - interpretation, not a diagnosis. A single out-of-range value is common and often benign; always discuss decisions with your doctor.